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What is gene synthesis ?

Update time : 2020-06-18

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What is gene synthesis ?

Gene synthesis is a technology that uses artificial methods to synthesize genes, and is one of the methods of gene acquisition. Compared with obtaining genes from existing organisms, gene synthesis does not require a template, so it is not limited by the source of genes.

Advantages of gene synthesis:

✦ The synthesis period is short, which can ensure that the sequence is correct.

✦ Gene synthesis has greater flexibility, and can modify the gene cleavage site and gene sequence to facilitate downstream cloning and experiments.

✦ Researchers have designed genes that are difficult to obtain or do not even exist in nature according to their wishes.

✦ Gene synthesis genes can be codon optimized so that the genes can be well expressed in various biological expression systems.

Application of gene synthesis:

✦ clone human mouse antibody or recombinant antibody

✦ Synthesize different gene mutant strains, SNPS, or other mutant strains

Design and synthesis of DNA vaccine

✦ Mass synthesis of cDNA for microchips

The application of gene synthesis technology has enabled society to make rapid progress and solve some major problems. For example, this new coronary pneumonia, gene synthesis technology can help us better understand the virus transmission and pathogenic mechanisms for the prevention of epidemics. , Diagnosis and treatment provide important information.